The invention discloses a device for comprehensively preventing one-ventilation and three-prevention accidents on a tunneling working plane. The device is installed in a return air tunnel of the tunneling working plane and within 30-50m from the working plane, and is used for preventing the tunneling working plane from accidents of fire disaster, flood, coal and gas outburst and the like. The device is characterized by being integrally fixed with walls of a roadway through a heavy support; the heavy support is solidly and integrally fixed with the walls of the roadway through an anchor rod anchor cable; two sets of steel-made heavy air doors are installed in front of and behind a heavy supported tunnel of the walls of the roadway and are solidly and integrally connected with the heavy support; emergency exits are installed on the steel-made heavy air doors; opening directions of the emergency exits are opposite to opening directions of the steel-made heavy air doors; the two sets of steel-made heavy air doors in a front and rear manner are controlled by a hydraulic machine; the hydraulic machine is controlled by a liquid level sensor; and when a flood accident happens to the tunneling working plane, the flood water level affects the liquid level sensor, the liquid level sensor controls the hydraulic machine, and the steel-made heavy air doors are quickly closed by the hydraulic machine.