The invention discloses a transmission shaft with anti-torque and vibration attenuation functions. The transmission shaft comprises a shaft tube, a connecting plate and a welding fork. One end of the welding fork is connected with the connecting plate, while the other end of the welding fork is inserted in the shaft tube. An inner wall of the shaft tube is connected with the welding fork through elastic materials. Since the shaft tube of a transmission shaft is connected with the welding fork through the elastic materials and original rigid connection of the shaft tube and the welding fork is replaced by elastic connection, vibration generated during power transmission of the transmission shaft is effectively reduced, and anti-torque and vibration attenuation performance is enhanced. Besides, the elastic materials are located between the shaft tube and the welding fork, the transmission shaft is compact in structure, so that plenty of spaces are saved in assembling, and assembly of full automobiles is facilitated.