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发明公开
CN103381161A 化合物SC-51089在制备治疗糖尿病及并发症的药物中的用途 无效 - 撤回

化合物SC-51089在制备治疗糖尿病及并发症的药物中的用途
摘要：
本发明公开了化合物SC-51089在制备孕激素受体PR的拮抗剂中的用途以及该化合物在制备治疗糖尿病及其并发症的药物中新用途。该化合物作为孕激素受体（progesterone receptor，简称PR）选择性拮抗剂，一方面具有保护胰岛细胞阻止其功能退化的功能，另一方面可适当提高胰岛素分泌而不致产生高胰岛素血症。因此，化合物SC-51089可用于糖尿病及其并发症等疾病的治疗。
摘要（英）：

The invention discloses an application of a compound SC-51089 to prepare an antagonist of a progesterone receptor (PR), and a new application of the compound to prepare medicaments for treating diabetes and complications thereof. As the selective antagonist of the progesterone receptor (PR), on one hand the compound has the function of protecting islet cells and preventing islet cells from function degeneration, on the other hand the compound helps to properly improve insulin secreting to avoid generation of hyperinsulinemia. Therefore, the compound SC-51089 is applicable to diseases such as diabetes and the complications thereof and the like.

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