The invention discloses a method for producing a high-quality mulberry wine through fermentation. The mulberry juice is taken as the major raw material; the selected saccharomyces cerevisiae is adopted for direct fermentation to produce the raw mulberry wine; then the raw mulberry wine is subjected to pasteurization, ageing, clarification treatment, filtering and filling; finally, the high-quality mulberry wine product is obtained. The produced mulberry wine product is natural without any cane sugar, citric acid and the like; the mulberry wine is rich in nutrition, attractive in color and luster, fruity and soft, and mellow in taste.