The present invention relates to the field of drug synthesis, and discloses a compound, a preparation method and applications thereof. According to the present invention, the compound has the structure represented by a formula I or formula II, wherein RB is a compound residue having biological activity; the preparation method of the compound represented by the formula I or formula II has characteristics of easy performing, good reproducibility and low environmental pollution, and can be used for large scale preparation of the compound represented by the formula I or formula II; and the compound represented by the formula I or formula II is the compound having the completely-new structure, has effects of significant vasodilatation, anticoagulation and anti-ischemia-reperfusion injury, and can be used for preparation of drugs for prevention or treatment of cardiovascular and cerebrovascular diseases and anticoagulation drugs. The formula I and the formula II are defined in the instruction.