The invention discloses a dust removal device for a feed opening. The dust removal device comprises dust suction pipes arranged around the feed opening, wherein the side wall of each dust suction pipe is provided with a dust suction opening and a vacuum connector, and each dust suction opening is in a strip shape and is distributed around the feed opening. The dust removal device provided by the invention is wide in application range in chemical industry production, is well matched with the feed opening of a reaction kettle, is extremely convenient to install and disassemble, and can be immediately installed and disassembled, the idle problem of the device cannot be caused, and the utilization rate of the device is improved; meanwhile, the dust removal device has the advantages of simple structure, high dust removal efficiency and the like.