The invention provides an industrialized production method for synchronously producing stevioside, flavone and chlorogenic acid. The method includes the following steps that step1, stevia rebaudiana leaves are weighed, extracted by adding water and filtered to obtain an extracting solution, flocculating agents are added under the condition of heat preservation, the pH is adjusted to 7-12, standing is performed for 0-120 minutes at the temperature of 30 DEG C-75 DEG C, then filtering is performed to obtain filter mud and filter liquid, and resin purification is performed on the filter liquid so as to obtain the stevioside product; step2, the filter mud is extracted through acid solvent, and extracting solutions are merged and concentrated; step3, solvent is added into a concentrated solution for dilution, and macroporous adsorption resin is added for adsorption; step4, gradient resolution is performed on the macroporous adsorption resin in the step3, a low-concentration resolution liquid is concentrated and dried to obtain the chlorogenic acid product, and high-concentration resolution liquid is concentrated to be standby; step5, after water is added into the high-concentration resolution liquid for dilution, organic solvent the same as the high-concentration resolution liquid in volume is used for extraction, and organic phases are merged, concentrated and dried to obtain the flavone product. By the adoption of the method, the stevioside, flavone and chlorogenic acid are extracted at the same time, the production cost is lowered, and the comprehensive utilization value of the stevioside is increased.