The invention discloses health-care food with the effect of protecting alcoholic liver injury and a preparation method. The health-care food is prepared from 10-50 parts of taurine, 10-30 parts of chitosan oligosaccharides, 3-15 parts of chitosan and 10-50 parts of ganoderma extracts. According to the health-care food, the protection effect on the alcohol-injured liver is achieved, the MDA and TG content in the liver tissue can be decreased, the GSH content in the liver tissue can be increased, the fatty degeneration degree of the liver tissue can be reduced, deterioration of histological characteristics of the injured liver can be effectively prevented, repair and regeneration of the liver cells are promoted, and the organism immunity is improved.