The present invention provides a distance sensor method vector measurement method based on tetrahedron configuration. Three laser distance measuring sensors arranged in an equilateral triangle mode are installed on the end effector of a machine tool and a robot, and the end effector of the machine tool and the robot are configured to fix the measurement directions of the three laser distance measuring sensors, so that the laser beam is gathered into the same point and the end effector of the machine tool and the robot and the three laser distance measuring sensors form a space tetrahedron; the three position relations of the space tetrahedron top and the curved surface to be measure are employed, the three position relations include: the top is located in the curved surface, the top is located on the curved surface, and the top is located out of the curved surface, the normal vector n of the manufacture hole curved surface to be measured is obtained through combining the numerical value measured by the laser distance measuring sensors; and finally, the driving amount of each shaft of the machine tool or the robot is obtained to allow the control system to perform the posture alignment motion according to the normal vector information of the manufacture hole to be measured obtained by the measurement and calculation. The distance sensor method vector measurement method based on tetrahedron configuration is high in solution precision and is able to effectively and rapidly respond to the requirements of the control system.