The invention relates to the technical field of electric control guide rail platforms, in particular to a manual-automatic integrated control mobile platform. The mobile platform comprises a transverse translational movement mechanism and a longitudinal translational movement mechanism. The transverse translational movement mechanism comprises a transverse guide rail body, a top plate in sliding fit with the transverse guide rail body and a driving motor for driving the top plate to move transversely. The driving motor drives the top plate to move through a first screw assembly. The first screw assembly is further matched with a manual drive lead screw. The longitudinal translational movement mechanism comprises a base. The base is in sliding fit with the transverse guide rail body. The base is further provided with a second screw assembly for driving the transverse guide rail body to move. According to the manual-automatic integrated control mobile platform, manual control and electric control can be achieved, the structure is simple, operation is convenient, the requirement of a system for high precision and automation of equipment can be met, and the requirement on the stability of rapid linear movement of a collimator is met.