The invention discloses a cheese-core beef ball and a preparation method thereof. The cheese-core beef ball is elastic, soft, glutinous and easily chewable; the cheese-core beef ball can provide high-quality protein of beef, and besides, celery is added into beef stuffing to increase the content of dietary fiber and to allow nutrients to be balanced; the inner core of the ball uses cheese as a main material, so elemental calcium is added; and wolfberry is added to achieve nourishing and health-care effect. The cheese-core beef ball provided by the invention fills a gap in the field of balls targeted to the elder on the market at present.