The invention belongs to the technical field of transportation vehicles and particularly relates to cargo loading and unloading. A multifunctional loading-unloading mechanism comprises an auxiliary frame, a moving trolley, a swing arm mechanism and a loading-unloading arm, wherein the auxiliary frame is fixed to a chassis truck, and the moving trolley is fixed to the auxiliary frame and can perform linear back and forth movement. The swing arm mechanism is fixed to the moving trolley, the swing arm mechanism and members on the swing arm mechanism and can perform 360-degree rotation, and loading-unloading operation can be performed from the tail and side face of the truck. The loading-unloading arm adopts a multi-joint telescopic mode and is hinged to the front end of the swing arm mechanism. The multifunctional loading-unloading mechanism has the advantages of being comprehensive in loading-unloading function, high in mechanization degree, high in loading-unloading speed, good in applicability and the like.