The invention discloses a comprehensive analysis system for xerophthalmia. The comprehensive analysis system comprises an imaging system, an analyzing system and a video terminal, wherein the imaging system comprises a lighting source, an imaging assembly, a control panel and a camera shooting module, the lighting source penetrates through the imaging assembly and irradiates the eyes of a patient, and the camera shooting module carries out imaging on the eyes of the patient, and transmits the generated image to a PC machine through a USB interface; the analyzing system is arranged at the PC machine end, and comprises a communication module, an image data collecting module, a tear film breakup time check module, a lacrimal rivus height measuring module, a meibomian gland image collecting and enhancing module, a lipid layer analyzing module, a data analyzing module and an information management output module; the video terminal is connected with the analyzing system. With the comprehensive analysis system for xerophthalmia provided by the invention, the functions of tear film breakup time statistics checking, lacrimal rivus height measurement, meibomian gland image collection and enhancement, human eye lipid layer analysis, and the like are realized, a basis is provided for the clinical diagnosis for xerophthalmia, and the comprehensive analysis system is applied to the medical treatment in the relevant fields of clinical diagnosis of the ophtalmology department.