The invention provides an integrated full-automatic nucleic acid detection reaction system. The system can automatically complete such operations as sample information acquisition, automatic sampling, liquid automatic transferring, oscillating and uniform mixing, nucleic acid extraction and the like in a nucleic acid extracting process, so as to avoid interference of a manual operation in the extracting process to a test result and to bring about benefits for improving the effectiveness, accuracy and extracting efficiency of experiments. A liquid suction mechanism in the system comprises multi-channel independent devices; the liquid suction mechanism, in coordination with a transverse liquid transferring mechanism and a longitudinal liquid transferring mechanism, can independently operate one channel or simultaneously operate a plurality of channels; a single operation can be conducted, and meanwhile, a plurality of operations can be simultaneously conducted as well; and when conducting the single operation, each sample can be independently tracked conveniently, and when simultaneously implementing the plurality of operations, in accordance with program setting, independent operations of a remainder can be conducted when the number of the experiments is not integral multiple of channels of a sampling and liquid transferring device, so that the adaptivity and the flexibility of the experiments are greatly enhanced.