The invention relates to a high-precision online dynamic continuous adjustable output power source which comprises a microprocessor, a digital potentiometer, an operational amplifier, a simulation collection chip and a power supply chip. The microprocessor is connected with the simulation collection chip and the digital potentiometer and used for receiving a voltage value collected by the simulation collection chip to obtain a current voltage setting pin resistance of the power supply chip, the digital potentiometer is configured through an SPI interface, the output end of the digital potentiometer is connected with the operational amplifier and the power supply chip and used for changing the resistance of a voltage regulation pin of the power supply chip, the output end of the operational amplifier is connected with the simulation collection chip and used for collecting the voltage value corresponding to the voltage setting pin resistance of the power supply chip to achieve real-time monitoring of resistance setting, the simulation collection chip is used for collecting the voltage value converted by output resistance of the digital potentiometer in real time, and transmitting the collected voltage value to the microprocessor chip through the SPI interface, and full-closed loop control is achieved, and the output end of the power supply chip is made to output the needed output power supply by regulating the resistance of the voltage setting pin.