The invention provides an inhibitor for Bruton's tyrosine kinase. The inhibitor is a compound of a formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrugs of the compound in the formula (I). The invention further provides medicine composition comprising the compound. The invention further provides a method and an application using the inhibitor for the Bruton's tyrosine kinase to inhibit activity of tyrosine kinase or treat diseases, disorders or symptoms benefiting from inhibition of the activity of the Bruton's tyrosine kinase.