The present invention discloses a new cardiac pump model-based variable rotation speed control method and belongs to the artificial heart control field. According to the method of the invention, the mathematical model of the rotational speed, flow rate and pressure of a cardiac pump is constructed according to the hydraulic characteristics and similarity theorem of a rotary cardiac pump. According to the model-based control method, the mathematical model and modern detection control technologies are combined; blood pressure and flow signals are acquired; suction and reflux degrees are determined by using a suction and reflux detector; and a rotation speed feedback control method is determined on the basis of a physiological reference model. Based on the working principle of the rotary pump, the mathematical model of the rotary pump is built. With the mathematical model-based cardiac pump variable rotation speed control method adopted, the working state of the cardiac pump can be effectively detected, suction or reflux can be eliminated timely, and the reliability of the cardiac pump system can be improved.