The invention relates to a SoC (System on a Chip) application guidance method with a self-detection function. Before an application is operated, the application is moved to an SRAM (Static Random Access Memory) from FLASH, the PC (Program Counter) pointer of a CPU (Central Processing Unit) is endowed with the first line of instruction address of the application, and one guidance function module operated by the application is started. By use of the program guidance method, before the application is transported, the SRAM operated by the application is checked, application transportation correctness is checked, and an operation target and the correctness of the operation environment of the operation target are guaranteed before the application is operated. By use of the method, through program uploading consistency checkout and checkout before and after transportation, correctness from a source program to the operation of the program each time is guaranteed, the function of the operation environment is guaranteed to be complete, and fault positioning can be quickly carried out once a program fails.