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发明授权
CN107335049B 菊科类型环肽化合物作为cGAS-STING信号通路抑制剂的应用 有权

菊科类型环肽化合物作为cGAS-STING信号通路抑制剂的应用
摘要：
本发明公开了一种菊科类型环肽化合物或其药理学上容许的盐作为cGAS‑STING信号通路抑制剂的应用，以及菊科类型环肽化合物或其药理学上容许的盐作为cGAS‑STING信号通路抑制剂在制备治疗cGAS‑STING信号通路异常激活的疾病的药物中的应用。由于本发明所述的菊科类型环肽化合物为天然化合物，其剂型和用药方式多样化，具有广泛的临床应用前景。
摘要（英）：

Disclosed are the use of a Compositae-type cyclic peptide compound or a pharmacologically acceptable salt thereof as a cGAS-STING signalling pathway inhibitor, and the use of the Compositae-type cyclic peptide compound or a pharmacologically acceptable salt thereof as a cGAS-STING signalling pathway inhibitor in the preparation of a drug for treating a disease where the cGAS-STING signalling pathway is abnormally activated. The Compositae-type cyclic peptide compound is a natural compound with diversified dosage forms and methods of administration and has wide clinical application prospects.

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