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CN107417687A 五元杂环并[3,4-d]哒嗪酮类化合物、其制备方法、药物组合物及其应用 无效 - 撤回

五元杂环并[3,4-d]哒嗪酮类化合物、其制备方法、药物组合物及其应用
摘要：
本发明提供了一种作为FGFR激酶抑制剂的五元杂环并哒嗪酮类化合物及其制备和应用，具体地，本发明提供了一种如下式(I)所示的化合物；其中，各基团的定义如说明书中所述。本发明的化合物具有很好的FGFR激酶抑制活性，可以用于制备一系列治疗FGFR激酶活性相关的疾病的药物。
摘要（英）：

The invention provides a five-membered heterocyclo[3,4-d]pyridazinone compound used as a FGFR kinase inhibitor, as well as preparation and application thereof, and particularly provides the compound represented as the formula (I), wherein the groups are defined as the specification. The compound has great FGFR kinase inhibiting activity and can be used for preparing a series of medicines for treating diseases related to activity of the FGFR kinase.

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