The invention discloses a multi-state multi-dimensional constraint locking mechanism. The multi-state multi-dimensional constraint locking mechanism includes an active end, a left passive end and a right passive end. The left passive end and the right passive end each include a bearing pin and a bearing ring. The active end includes a lead screw, a T-shaped nut moving along the lead screw and a bottom plate. The two sides of the T-shaped nut are correspondingly provided with a left sliding assembly and a right sliding assembly which move correspondingly along a left guiding rail and a right guiding rail. The two sides of the bottom plate are further correspondingly provided with a left locking hook and a right locking hook which are in abutting contact with the T-shaped nut and can lock the bearing rings. The T-shaped nut moves along the lead screw. The state that bearing sleeves and the bearing pins are nested or detached and the state that the left locking hook, the right locking hook and the bearing rings are locked or disengaged can generate. Therefore, the active end, the left passive end and the right passive end are arranged at the splicing position between an open cabin door and a door frame, locking multi-dimensional locking constraint of three parts in two directions can be achieved, and multi-state locking constraint of two locking states and an unlocking state can also be achieved.