The invention relates to a Chinese and western medicine composition for treating ischemic cerebral stroke, and a preparation method of the Chinese and western medicine composition. The Chinese and western medicine composition is prepared from the following effective component raw materials: spinach beet, radix salviae miltiorrhizae, herba asplenii prolongati, radix triplostegiae grandiflorae, herbof prolongated spleenwort, herba lycopodii obscuri, radix campylotropis macrocarpae, radix et rhizoma dispori cantoniensis, caulis cucurbitae, radix seu caulis verntilaginis leiocarpae, spinach herbwith root, radix rubiae yunnanensis, nafronyl and betahistine. By combining the Chinese herbal medicines with functions of activating blood and removing stasis, replenishing blood and promoting bloodcirculation, relaxing muscles and tendons and removing obstruction from meridians, dispelling wind and eliminating dampness, softening hard masses and removing qi stagnation as well as calming liver and tranquilizing mind, the Chinese and western medicine composition achieves a synergistic effect and can soften blood vessels and promote blood circulation; furthermore, by combining the two westernmedicines, i.e. the nafronyl and the betahistine, the effect of expanding the blood vessels is further enhanced, so that the Chinese and western medicine composition has a function of protecting the heart, liver, spleen, kidney and other visceral organs of patients with the ischemic cerebral stroke when being used for treating the ischemic cerebral stroke; the Chinese and western medicine composition is obvious in curative effect and quick in response when being used for treating the ischemic cerebral stroke; in the aspect of prescription selection, the Chinese and western medicine compositionhas certain innovativeness in cataract treatment and has certain social economic value.