In the invention, metal salt and aluminum salt, which have special ratio and contain an active component, are employed; meanwhile, with a coprecipitation agent, which includes NaOH and Na2CO3 in special ratio, is employed; the components are aged at a certain temperature to prepare a catalyst precursor in a hydrotalcite structure. The catalyst precursor then is calcined and reduced to prepare thecatalyst active component, which is narrow in particle size distribution and small in particle size of the nano-particles, so that catalytic activity of the catalyst in a polyether polyol reductive amination reaction, thereby producing the high-effective catalyst which is used for synthesizing primary amino-terminated polyether. The catalyst is used for reducing and aminating the polyether polyolto produce the primary amino-terminated polyether, reaction conversion rate and product selectivity being high. In addition, the catalyst has simple components and low cost and is suitable for being promoted on market. An experiment proves that the catalyst can reach 99.6% in reaction conversion rate and reach 99.7% in selectivity on the primary amino-terminated polyether.