The invention relates to a desk type active vibration isolation control system and belongs to the electronic instrument field. The desk type active vibration isolation control system includes a low-frequency expansion circuit, an analog-to-digital conversion circuit, a digital-to-analog conversion circuit, a communication interface circuit, a DSP and CPLD combined structure-based main control circuit and a driving circuit. The vibration isolation system has a large vibration isolation bandwidth, a higher vibration attenuation rate and can achieve vibration isolation of six degrees of freedom.The vibration isolation control system has the advantages of simple structure, strong bearing capacity, convenient installation, high cost performance, fast response and the like, and can be used alone (the joint use of a plurality of systems is not needed).