The invention discloses a saccharomyces pastorianus strain with high oxidation resistance, and belongs to the field of bioengineering. Saccharomyces pastorianus is preserved in the General Microorganism Center of the China Committee for Culture Collection of Microorganisms on March 23rd, 2018, a preservation number of the saccharomyces pastorianus is CMCC No.15504, and a preservation address is the Institute of Microbiology of the Chinese Academy of Science in No. 3 of the First Yard on the Beichen West Road in the Chaoyang District in Beijing. The saccharomyces pastorianus strain has the advantage that the saccharomyces pastorianus strain is good in production stability and can be used for producing beer.