The invention discloses a multi-axis linkage drilling and cutting device. The device is characterized by comprising a shell, a main power transmission mechanism, an auxiliary power transmission mechanism and an auxiliary chuck, and the shell can fix the main power transmission mechanism and the auxiliary power transmission mechanism; and the auxiliary chuck is arranged on the main power transmission mechanism or the auxiliary power transmission mechanism, and can move along with the main power transmission mechanism or the auxiliary power transmission mechanism, and the auxiliary chuck can fixa drill bit or a milling cutter; and the main power transmission mechanism can rotate to drive the auxiliary power transmission mechanism to rotate. The main power transmission mechanism can rotate to drive the auxiliary power transmission mechanism to rotate, then the auxiliary chuck on the main power transmission mechanism or on the auxiliary power transmission mechanism can be driven to rotate, then the drill bit or the milling cutter on the auxiliary chuck can be driven to work, so that simultaneous machining of a plurality of holes is realized, the machining efficiency is high, and position precision between the holes is high.