A system and method for planning a pathway through an anatomical luminal network of a patient including memory storing a computer program configured to analyze and manipulate CT images, a processor configured to execute the computer program, and a display device configured to display a user interface of the computer program. The user interface includes a CT image window configured to display a slice of CT image data, a localizer window configured to display an image of at least one lung, the localizer window including a localizer configured to identify a location of the displayed slice relative to the at least one lung, and a target selection element configured to select a target from a displayed slice of CT image data in response to a user input.