The invention relates to an industrial binocular camera and infrared thermal imager combined calibration device and method, and the method comprises the steps: taking an inner corner point of a ZhangZhengyou calibration plate in a standard format as a circle center, forming a small hole, and enabling the radius of the small hole to be smaller than a half of the side length of a black-white grid;incandescent bulbs are installed in the small holes, and bases of the incandescent bulbs are communicated with a power source through adjusting devices. A sensor support is erected above the Zhang Zhengyou calibration plate, an industrial binocular camera and an infrared thermal imager are installed on the sensor support, and visual angles of the industrial binocular camera and the infrared thermal imager coincide when the industrial binocular camera and the infrared thermal imager shoot calibrated devices; the invention has the advantages of simple design, simple operation and low cost, and can calibrate the two cameras at the same time.