The invention discloses an N-((2-phenyl imidazo[1,2-a]pyridine-3-yl)methyl)phenylamine compound and a synthesis method thereof. The synthesis method includes the following steps that in an air environment, 2-phenyl-imidazo[1,2-a]pyridine and a phenylamine compound are added into a reaction tube, di-tert-butyl peroxide, potassium permanganate, sodium tert-butoxide and solvents are sequentially added, and reaction is conducted for 8-12 hours at 100-140 DEG C; and after the reaction is completed, a target product is obtained through chromatographic separation and drying. According to the reaction, methanol and hexafluoroisopropanol are used as the reaction solvents, so that amino methylation of the imidazo[1,2-a]pyridine compound and phenylamine is achieved, the method is simple and efficient, the cost is low, purification is easy, substrate adaptability is wide, and functionalization reaction types of the imidazo[1,2-a]pyridine compound are enriched; the method has important significancefor research and application of amino methylation of the imidazo[1,2-a]pyridine compound.