The invention provides a synthesis method of a double bond-terminated compound. The synthesis method includes the steps of: 1) taking a compound with an active hydrogen group on a primary carbon and/or secondary carbon position as the substrate, subjecting the substrate and epoxy isobutene to contact reaction for tertiary alcohol termination, thus obtaining a tertiary alcohol terminated product; and 2) subjecting the tertiary alcohol terminated product to intramolecular dehydration under the action of a lewis acid catalyst, thus obtaining the double bond-terminated product. The synthesis method provided by the invention can improve the double bond termination rate, and the synthesis process is simple, controllable, green and environment-friendly.