The invention discloses a non-deliquescent high-purity chalcohalide glass and a purification preparation method thereof. The molar composition of the high-purity chalcohalide glass is represented by the following chemical formula: (Ge-As-Se)100-xIx, wherein x is 0-40. I is added to a Ge-As-Se chalcogenide glass matrix to obtain the component-optimized non-deliquescent high-purity chalcohalide glass. The invention also provides the purification preparation method of the non-deliquescent high-purity chalcohalide glass, capable of effectively removing impurities in the chalcohalide glass and reducing the deliquescence of the chalcohalide glass. The purification preparation method can effectively remove main oxygen-containing compounds and hydroxyl-containing compounds (including water) in thechalcohalide glass, and improves the purity of the chalcohalide glas while obtaining the non-deliquescent chalcohalide glass. The high-purity chalcohalide glass has a uniform optical quality and a good infrared transmittance, and can be used to prepare non-deliquescent high-purity chalcohalide glass optical fibers.