The invention provides a cooling fan with low harmonic noise. The cooling fan with the low harmonic noise comprises fan blades and stationary blades, wherein the fan blades comprise seven blades whichare non-uniformly distributed; the stationary blades are arranged to enable the fan blades to rotate relative to the stationary blades; the stationary blades comprise a first group of guide blades and a second group of guide blades; each group of the the guide blades comprises three guide blades uniformly distributed; and the second group of the guide blades is deflected at a guide blade deflection angle between 23 degrees to 25 degrees relative to the first group of the guide blades. According to the cooling fan, discrete noise can be effectively reduced as a whole, so that the driving comfort of an automobile is improved.