The invention discloses an urban logistics system and method based on a Scrapy frame and a four-rotor aircraft. A hardware platform of the four-rotor aircraft comprises an inertial navigation unit, amulti-degree-of-freedom camera holder, a distance measuring module, a GPS positioning module and a communication module. A data acquisition module mainly comprises a sensor real-time acquisition module and a network information crawling module; an image recognition module is used for analyzing image data acquired by the camera holder, and for marking and positioning, alarming and early warning, carrying out OCR text recognition on an express note by calling a hundred-degree API, acquiring a geographical position, converting the geographical position into longitude and latitude information to obtain an order form destination position, and distributing an instruction signal to a flight control module; the flight control module is used for carrying out attitude calculation on the data acquired by an inertial navigation unit and enabling the aircraft to fly autonomously according to the instruction signal of a control base station; and the control base station and the aircraft adopt two-way communication. According to the invention, the efficiency of the unmanned aerial vehicle logistics system can be improved.