The invention provides a PCB spray printing machine and a PCB spray printing production line. The PCB spray printing machine comprises an ink jet system, a horizontal conveyor belt for conveying a PCBand a liftable worktable; when the PCB is fed, the liftable worktable is located below the horizontal conveyor belt; when the PCB moves to the position above the liftable worktable along with the horizontal conveyor belt, the liftable worktable supportsthe PCB to ascend to be separated from the horizontal conveyor belt and fix the PCB to the liftable worktable; the ink jet system conduct spray printing on the PCB; after spray printing is carried out, the liftable worktable descends, and the PCB descends to the horizontal conveyor belt to be continuously conveyed along with the horizontal conveyor belt. As the PCB is conveyed on the horizontal conveyor belt and is subjected to spray printing on the liftable worktable, automatic assembly line production of spray printing of the PCB is achieved, so that the production efficiency is high. The PCB spray printing machine is high in positioning precision and avoids positioning errors caused by a manipulator and a truss structure in the priorart. Deformation, dimension and shape errors of an image are compensated by using four CCD cameras, so that the positioning and printing precision is further improved.