The invention provides an ignition chamber type engine with a high-energy ignition fuel and a control method thereof, and belongs to the field of engines. The ignition chamber type engine includes a combustion chamber, a gas intake system, an exhaust system, a fuel supply system, a high-energy ignition fuel supply system, a fuel nozzle, a high-energy ignition fuel nozzle, an ignition chamber, andan electronic control system. By arranging the ignition chamber with the ignition-chamber high-energy ignition fuel nozzle and an ignition device, the high-energy ignition fuel supply system supplieshigh-energy ignition fuel into the ignition chamber through the ignition chamber high-energy ignition fuel nozzle, the ignition device ignites the high-energy ignition fuel, an action of an ignition chamber jet flow and the characteristics of the high-energy ignition fuel are fully utilized, ignition energy and ignition stability are greatly enhanced, and efficient clean combustion is realized; and a high-efficiency clean combustion in the full working condition range of the engine is realized through a various-work condition control.