The utility model belongs to the technical field of medical testing equipment, a automatic laser beam perforating equipment of dry blood cake is provided, be in with the setting including laser assembly the blood cake receiver of laser assembly below, and control laser assembly is to laying blood cake filter paper on the blood cake receiver punches and makes the sample enter into a control assembly and drive in the blood cake receiver blood cake receiver directional motion's the 2nd control assembly, the blood cake receiver includes a plurality of holding lists of separating each other and be used for the exemplar of sample holds chamber, a plurality of it is just right that the exemplar holds the chamber laser assembly, the drive of the 2nd control assembly the blood cake receiver removes and makes laser assembly progressively correspond all the exemplar holds the chamber, can to solve current sample mode degree of automation low in the design like this to the problem that still has sample room cross contamination.