发明公开
- 专利标题： POLYPEPTIDE FRACTION FROM MUSSEL FOR MEDICAL USE
- 专利标题（中）： 多肽组用作抗菌药物。
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申请号： EP81901117.0申请日： 1981-04-29
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公开(公告)号： EP0050636A1公开(公告)日： 1982-05-05
- 发明人: ROTHMAN, Ulf Sven Erik
- 申请人： PHARMACIA AB
- 申请人地址： Box 181 S-751 04 Uppsala SE
- 专利权人： PHARMACIA AB
- 当前专利权人： PHARMACIA AB
- 当前专利权人地址： Box 181 S-751 04 Uppsala SE
- 代理机构： Krause, Dieter
- 优先权： SE19800003253 19800429; SE19800003256 19800429
- 国际公布： WO1981003124 19811112
- 主分类号： A61K35
- IPC分类号： A61K35 ; A61K38 ; A61K39 ; C07K14 ; C07K16
摘要：
PCT No. PCT/SE81/00130 Sec. 371 Date Dec. 23, 1981 Sec. 102(e) Date Dec. 23, 1981 PCT Filed Apr. 29, 1981 PCT Pub. No. WO81/03124 PCT Pub. Date Nov. 12, 1981.The invention relates to certain polypeptide fractions for use as an anti-microbial drug, drug compositions containing such polypeptide fractions, methods of reducing the infectivity possibilities of microbes by administering the polypeptide fractions, methods of preparing antisera using the polypeptide fraction, and a method of preparing the polypeptide fraction. The polypeptide fractions are characterized in that they are isolated from the body fluids of mussels, in particular Mytilus species such as blue mussel (Mytilus edulis), and in that they are capable of biospecifically binding sialic acid. The polypeptide fractions are active against a broad spectrum of viruses, bacteria and protozoa.
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