公开(公告)号：EP0050636A1

公开(公告)日：1982-05-05

申请号：EP81901117.0

申请日：1981-04-29

申请人： PHARMACIA AB

发明人： ROTHMAN, Ulf Sven Erik

IPC分类号： A61K35 ,  A61K38 ,  A61K39 ,  C07K14 ,  C07K16

CPC分类号： C07K16/18 ,  A61K35/618 ,  A61K38/00 ,  C07K14/435 ,  Y02A50/491 ,  Y10S530/857

摘要： PCT No. PCT/SE81/00130 Sec. 371 Date Dec. 23, 1981 Sec. 102(e) Date Dec. 23, 1981 PCT Filed Apr. 29, 1981 PCT Pub. No. WO81/03124 PCT Pub. Date Nov. 12, 1981.The invention relates to certain polypeptide fractions for use as an anti-microbial drug, drug compositions containing such polypeptide fractions, methods of reducing the infectivity possibilities of microbes by administering the polypeptide fractions, methods of preparing antisera using the polypeptide fraction, and a method of preparing the polypeptide fraction. The polypeptide fractions are characterized in that they are isolated from the body fluids of mussels, in particular Mytilus species such as blue mussel (Mytilus edulis), and in that they are capable of biospecifically binding sialic acid. The polypeptide fractions are active against a broad spectrum of viruses, bacteria and protozoa.