发明公开
EP0153171A3 New 2-hydroxyethyl-trimethylammonium salt of 1-ethyl-3-carboxy-4-oxo-6,7-methylenedioxy-1,4-dihydroquinoline, process for the preparation thereof and pharmaceutical composition containing it
失效
1-乙基-3-羧基-4-氧代-6,7-亚甲基-1,4-二氢喹啉的新2-羟基乙基 - 三甲基铵盐，其制备方法和含有其的药物组合物
- 专利标题： New 2-hydroxyethyl-trimethylammonium salt of 1-ethyl-3-carboxy-4-oxo-6,7-methylenedioxy-1,4-dihydroquinoline, process for the preparation thereof and pharmaceutical composition containing it
- 专利标题（中）： 1-乙基-3-羧基-4-氧代-6,7-亚甲基-1,4-二氢喹啉的新2-羟基乙基 - 三甲基铵盐，其制备方法和含有其的药物组合物
-
申请号： EP85301030申请日： 1985-02-15
-
公开(公告)号： EP0153171A3公开(公告)日： 1985-10-30
- 发明人: Szentmiklosi, Peter , Szuts, Tamas , Lengyel, Jozsef , Horvath, Gabor , Marmarosi, Katalin
- 申请人： CHINOIN Gyogyszer és Vegyészeti Termékek Gyßra RT.
- 专利权人： CHINOIN Gyogyszer és Vegyészeti Termékek Gyßra RT.
- 当前专利权人： CHINOIN Gyogyszer és Vegyészeti Termékek Gyßra RT.
- 优先权： HU60784 19840216
- 主分类号： C07D491/04
- IPC分类号： C07D491/04 ; C07C91/26 ; A61K31/47 ; C07D317/00 ; C07D221/00
摘要：
The invention relates to the new 2-hydroxyethyl-trimethyl-ammonium salt of 1-ethyl-3-carboxy-4-oxo-6,7-methyl- erseriioxy-1,4-dihydroquinoline having ureterodisinfecting ac- tirvity, which is prepared by reacting 1-ethyl-3-carboxy-4-oxo--6,7-methylenedioxy-1,4-dihydroquinoline with the aqueous or ethanolic or with the aqueous-ethanolic solution of 2-hydroxyethyl-trimethylammonium hydroxyde. The new salt is water-soluble and well resorbed after oral administration. Thus, it is useful both in the human and the veterinary medicine.
信息查询
