发明公开
EP0155192A2 cDNA clones coding for polypeptides exhibiting IgE binding factor activity
失效
CDNS克隆编码包含多肽的IgE结合因子活性。
- 专利标题： cDNA clones coding for polypeptides exhibiting IgE binding factor activity
- 专利标题（中）： CDNS克隆编码包含多肽的IgE结合因子活性。
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申请号： EP85301834.9申请日： 1985-03-15
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公开(公告)号： EP0155192A2公开(公告)日： 1985-09-18
- 发明人: Martens, Christine L. , Ishizaka, Kimishige , Moore, Kevin W. , Huff, Thomas F.
- 申请人： Schering Biotech Corporation , THE JOHNS HOPKINS UNIVERSITY
- 申请人地址： 901 California Avenue Palo Alto California 94304-1104 US
- 专利权人： Schering Biotech Corporation,THE JOHNS HOPKINS UNIVERSITY
- 当前专利权人： Schering Biotech Corporation,THE JOHNS HOPKINS UNIVERSITY
- 当前专利权人地址： 901 California Avenue Palo Alto California 94304-1104 US
- 代理机构： Ritter, Stephen David
- 优先权： US590430 19840316
- 主分类号： C12P21/02
- IPC分类号： C12P21/02 ; C12N15/12 ; A61K37/02
摘要：
Plasmid vectors are provided that carry complementary DNA (cDNA) clones coding for polypeptides exhibiting mammalian IgE binding factor activity. One of these clones contains an open reading frame consisting of 556 codons. The cDNA is derived for example from messenger RNA isolated from a rat/mouse T-cell hybridoma line. The cDNA can be cloned by incorporation into a pcD plasmid vector. The plasmid vector also contains DNA segments from th SV40 virus, permitting expression of the cDNA to form a polypeptide having IgE potentiating activity after transfection into a mammalian host cell, such as monkey Cos7 cells.
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