发明公开
- 专利标题: Antibody-therapeutic agent conjugates
- 专利标题(中): 治疗安全性
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申请号: EP85401776.1申请日: 1985-09-13
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公开(公告)号: EP0175617A2公开(公告)日: 1986-03-26
- 发明人: Goers, John Walter , Lee, Chyi , Siegel, Richard Charles , McKearn, Thomas Joseph , King, Hurley Dalton , Coughlin, Daniel James , Rodwell, John Dennis , Alvarez, Vernon Leon
- 申请人: CYTOGEN CORPORATION
- 申请人地址: 201 College Road East Forrestal Research Center Princeton New Jersey 08540 US
- 专利权人: CYTOGEN CORPORATION
- 当前专利权人: CYTOGEN CORPORATION
- 当前专利权人地址: 201 College Road East Forrestal Research Center Princeton New Jersey 08540 US
- 代理机构: Warcoin, Jacques
- 优先权: US650754 19840913; US650375 19840913
- 主分类号: A61K39/395
- IPC分类号: A61K39/395
摘要:
This invention relates to antibody-therapeutic agent conjugates having a therapeutic agent covalently attached to an antibody or antibody fragment. Also described are methods for intermediates in the preparation of antibody conjugates. Therapeutic in vivo methods utilizing such antibody-therapeutic agent conjugates are described. Additionally novel photosensitizers suitable for use in preparing antibody-therapeutic agents are also described.
公开/授权文献
- EP0175617B1 Antibody-therapeutic agent conjugates 公开/授权日:1991-10-30
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