式II 其中R 1是如下的磺酰苯烷基胺具有低级烷基1-6个碳原子，具有3-7个C原子的芳烷基，芳烯基或芳基的环烷基，其中，在每种情况下，芳基部分单或多取代 可被卤素，C1-C6烷基，C1-C6烷氧基，羟基，三氟甲基，被取代的氰基，硝基，氨基，C1-C6烷基氨基，C2-C12Dialkylamino，C1-C6酰基氨基，C1-C16酰基或叠氮基，R 2表示氢 代表具有1-6个碳原子，酰基，芳烷基或芳烯基基团，其中芳基部分各自可以是单 - 或多卤素取代的烷基基团，C1-C6烷基，C1-C6烷氧基，羟基，三氟甲基，氰基，硝基 氨基，C1-C6烷基氨基，C2-C12Dialkylamino，C1-C6酰基氨基，C1-C16酰基或叠氮化物可以是取代的，B是直链或支链的亚烷基链具有最大4个碳原子的并且a是具有1-6个原子的烷基或链烯基 表示C1-C6甲酰基，C1-C6羟烷基或基团-D-R 3，其中D 一个 - ？ - 或 - ?? - 基团和R 3为氢，C1-C5烷基，C1-C5羟基烷基，或C1-C5烷基羧酸基团，它们的药理学上可接受的盐，酯，酰胺和内酯，对流程为 其制备方法，和药物用于治疗疾病，其是基于在肾功能的血小板聚集或改变。

Sulfonyl phenylalkylamines of formula II

• in which
• R, a lower alkyl group having 1-6 C atoms,
• a cycloalkyl radical having 3-7 C atoms.
• an aralkyl, aralkenyl or aryl radical, wherein the aryl moiety in each case one or more times by halogen, C ₁ -C ₆ alkyl, C ₁ -C ₆ alkoxy, hydroxyl, trifluoromethyl, cyano, nitro, amino, C ₁ -C ₆ alkylamino , C ₂ -C ₁₂ dialkylamino, C ₁ -C ₆ acylamino, C ₁ -C ₁₆ acyl or azide may be substituted,
• R ₂ is hydrogen,
• an alkyl group having 1-6 C atoms,
• an acyl group, represents an aralkyl or aralkenyl radical, the aryl moiety in each case being one or more times by halogen, C ₁ -C ₆ alkyl, C ₁ -C ₆ alkoxy, hydroxyl, trifluoromethyl, cyano, nitro, amino, C ₁ -C ₆ alkylamino, C ₂ -C ₁₂ dialkylamino, C, -C ₆ acylamino, C ₁ -C ₁₆ acyl or azide may be substituted,
• B an unbranched or branched alkylene chain with a maximum of 4 carbon atoms and
• A is an alkyl or alkenyl group having 1-6 atoms, a C ₁ -C ₆ Formylalkylgruppe, a C ₁ -C ₆ hydroxyalkyl or a radical -DR ₃ in which D represents a - -or- - Group and R ₃ is hydrogen, a _C1-C5 alkyl, a C, -C _s hydroxyalkyl or a C ₁ -C ₅ alkylcarboxylic acid residue,
• their pharmacologically acceptable salts, esters, amides, and lactones, to processes for their preparation as well as medicaments for the treatment of diseases which are based on a platelet aggregation or changes in renal function.