发明公开
- 专利标题: Botulinus toxin neutralizer
- 专利标题(中): BOTULINUS毒素中和剂
-
申请号: EP87300962.5申请日: 1987-02-03
-
公开(公告)号: EP0235957A3公开(公告)日: 1990-01-17
- 发明人: Nagai, Yoshitaka , Takamizawa, Koutaro , Tanaka, Ryuichiro , Takayama, Hiroo , Sakurai, Toshizo , Mutai, Masahiko
- 申请人: KABUSHIKI KAISHA YAKULT HONSHA
- 申请人地址: 1-19, Higashishinbashi 1-chome Minato-ku Tokyo 105 JP
- 专利权人: KABUSHIKI KAISHA YAKULT HONSHA
- 当前专利权人: KABUSHIKI KAISHA YAKULT HONSHA
- 当前专利权人地址: 1-19, Higashishinbashi 1-chome Minato-ku Tokyo 105 JP
- 代理机构: Brewer, Leonard Stuart
- 优先权: JP20066/86 19860203
- 主分类号: A61K31/20
- IPC分类号: A61K31/20
摘要:
A botulinus toxin neutralizer comprises at least one fatty acid having at least 12 carbon atoms. Such a fatty acid may be a saturated fatty acid such as lauric acid, myristic acid, palmitic acid, stearic acid, nonadecanoic acid, arachidic acid or behenic acid, or an unsaturated fatty acid such as oleic acid. The toxin neutralizer acts as if it were an antagonistic receptor for botulinus toxin and, when encountering botulinus toxin in the human body, it combines directly with the toxin and prevents the toxin from combining with the neuromuscular tissues of the human body. Hence the neutralizer prevents the outbreak of botulism. The toxin thus neutralized and affixed to the botulinus toxin is excreted from the human body. The botulinus toxin neutralizer can be manufactured easily and economically from a naturally occurring glyceride and is thus far less costly than the known antitoxin of ganglioside GTlb produced from bovine brain.
公开/授权文献
- EP0235957B1 Botulinus toxin neutralizer 公开/授权日:1993-04-07
信息查询
IPC分类: