发明授权
- 专利标题： PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES
- 专利标题（中）： 制备2-氧代-3-芳族碳酸衍生物。
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申请号： EP89910209.9申请日： 1989-09-11
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公开(公告)号： EP0407588B1公开(公告)日： 1993-12-08
- 发明人: HIRAI, Kenji , NAKAMURA, Kazumi , FUJITA, Atsuko
- 申请人： SAGAMI CHEMICAL RESEARCH CENTER
- 申请人地址： 4-5, Marunouchi 1-chome Chiyoda-ku Tokyo 100 JP
- 专利权人： SAGAMI CHEMICAL RESEARCH CENTER
- 当前专利权人： SAGAMI CHEMICAL RESEARCH CENTER
- 当前专利权人地址： 4-5, Marunouchi 1-chome Chiyoda-ku Tokyo 100 JP
- 代理机构： Kraus, Walter, Dr.
- 优先权： JP227414/88 19880913; JP283809/88 19881111; JP283810/88 19881111; JP156114/89 19890310; JP156115/89 19890310; JP156116/89 19890310
- 国际公布： WO9002725 19900322
- 主分类号： C07C59/84
- IPC分类号： C07C59/84 ; C07C59/86 ; C07C59/90 ; C07C51/347
摘要：
The invention relates to a process for producing a 2-oxo-3-aromatic carboxylic acid derivative, which comprises reacting an aromatic pyruvic acid derivative with an electrophilic compound in a protic solvent in the presence of a base. This process can provide in good yields the 2-oxo-3-aromatic carboxylic acid derivatives which can be easily converted to aromatic amino acid derivatives or 2-aromatic alkanoic acid derivatives which are important intermediates for synthesizing medicines, agrochemicals, etc.
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