发明公开
EP0411664A2 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives
失效
2-（2- Vinylpyrrolidinylthio）碳代青霉烯衍。
- 专利标题： 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives
- 专利标题（中）： 2-（2- Vinylpyrrolidinylthio）碳代青霉烯衍。
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申请号： EP90114980.7申请日： 1990-08-03
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公开(公告)号： EP0411664A2公开(公告)日： 1991-02-06
- 发明人: Nakagawa, Susumu, Banyu Pharmaceutical Co., Ltd. , Nakano, Fumio, Banyu Pharmaceutical Co., Ltd. , Otake, Norikazu, Banyu Pharmaceutical Co., Ltd. , Ushijima, Ryosuke, Banyu Pharmaceutical Co., Ltd.
- 申请人： Banyu Pharmaceutical Co., Ltd.
- 申请人地址： 2-3, 2-chome Nihonbashi Honcho Chuo-ku Tokyo JP
- 专利权人： Banyu Pharmaceutical Co., Ltd.
- 当前专利权人： Banyu Pharmaceutical Co., Ltd.
- 当前专利权人地址： 2-3, 2-chome Nihonbashi Honcho Chuo-ku Tokyo JP
- 代理机构： Wächtershäuser, Günter, Prof. Dr.
- 优先权： JP202568/89 19890804
- 主分类号： C07D477/00
- IPC分类号： C07D477/00 ; A61K31/40
摘要：
A compound of the formula:
wherein R 1 is a hydrogen atom or a methyl group, R 2 is a hydrogen atom or a lower alkyl group, each of R 3 , R 4 and R 5 is a hydrogen atom or a lower alkyl group, or R 3 and R 4 together form a methylene group, an ethylene group or a propylene group, or R 4 and R 5 form together with the adjacent nitrogen atom an aziridinyl group, an azetidinyl group, a pyrrolidinyl group, a piperidino group, a piperazinyl group or a morpholino group; or a pharmaceutically acceptable salt or ester thereof.
wherein R 1 is a hydrogen atom or a methyl group, R 2 is a hydrogen atom or a lower alkyl group, each of R 3 , R 4 and R 5 is a hydrogen atom or a lower alkyl group, or R 3 and R 4 together form a methylene group, an ethylene group or a propylene group, or R 4 and R 5 form together with the adjacent nitrogen atom an aziridinyl group, an azetidinyl group, a pyrrolidinyl group, a piperidino group, a piperazinyl group or a morpholino group; or a pharmaceutically acceptable salt or ester thereof.
公开/授权文献
- EP0411664B1 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives 公开/授权日：1995-01-18
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