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    2(2-Cyclopropylpyrrolidin-4-ylthio)-carbapenem derivatives
    2.
    发明公开
    2(2-Cyclopropylpyrrolidin-4-ylthio)-carbapenem derivatives 失效
    2-（2- Cyclopropylpyrrolidin -4-基硫基）carbapenemderivate。

    公开(公告)号：EP0435320A1

    公开(公告)日：1991-07-03

    申请号：EP90125679.2

    申请日：1990-12-28

    申请人： Banyu Pharmaceutical Co., Ltd.

    发明人： Nakagawa, Susumu, Banyu Pharmaceutical Co., Ltd. ,  Yamada, Koji, Banyu Pharmaceutical Co., Ltd. ,  Ushijima, Ryosuke, Banyu Pharmaceutical Co., Ltd.

    IPC分类号： C07D477/00 ,  A61K31/40

    CPC分类号： C07D477/20

    摘要： A compound of the formula:
    wherein R 1 Is a hydrogen atom or a methyl group, each of R 2 and R 3 which may be the seme or different, is a hydrogen atom or a lower alkyl group, or R 2 and R 3 form together with the adjacent nitrogen atom a heterocyclic group selected from the group consisting of an aziridinyl group, an azetidinyl group, a pyrrolldinyl group, a piperidlno group, a piperazinyl group and a morphollno group, A Is a carbonyl group or a single bond, and n ls an integer of from 0 to 3; or a pharmacautically acceptable salt or ester thereof.

    摘要翻译： 下式的化合物：其中R 1为氢原子或甲基，R 2和R 3可以相同或不同，为氢原子或低级烷基 基团或R 2和R 3与相邻的氮原子一起形成选自氮丙啶基，氮杂环丁烷基，吡咯烷基，哌啶子基，哌嗪基和吗啉代的杂环基 A为羰基或单键，n为0〜3的整数， 或其药学上可接受的盐或酯。