发明公开
- 专利标题： Piperidine compounds, method for preparation thereof, and a pharamceutical composition comprising the same
- 专利标题（中）： 哌啶类化合物，它们的制备方法和药物组合物。
-
申请号： EP91105567.1申请日： 1991-04-09
-
公开(公告)号： EP0451772A1公开(公告)日： 1991-10-16
- 发明人: Ito, Yasuo , Kato, Hideo , Koshinaka, Eiichi , Ogawa, Nobuo , Nishino, Hiroyuki , Sakaguchi, Jun
- 申请人： HOKURIKU PHARMACEUTICAL CO., LTD.
- 申请人地址： 1-Chome, 3-14, Tatekawacho, Katsuyama-shi Fukui-ken 911 JP
- 专利权人： HOKURIKU PHARMACEUTICAL CO., LTD.
- 当前专利权人： HOKURIKU PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： 1-Chome, 3-14, Tatekawacho, Katsuyama-shi Fukui-ken 911 JP
- 代理机构： Werner, Hans-Karsten, Dr.Dipl.-Chem.
- 优先权： JP93968/90 19900411; JP97522/90 19900416
- 主分类号： C07D409/04
- IPC分类号： C07D409/04 ; A61K31/445
摘要：
Novel piperidine compounds represented by the following formula (I):
wherein Y represents an alkylene group having 1 to 7 carbon atoms; A is a group represented by formula I-a or formula I-b:
wherein X represents -CH₂-S- or -S-; and R represents a hydrogen atom or a lower alkyl group with a proviso that A is a group represented by formula I-a, or R represents a hydrogen atom with a proviso that A is a group represented by formula I-b and pharmacologically acceptable salts thereof are disclosed. Also disclosed are a method for preparing the same; a pharmaceutical composition comprising the same; an antiallergic agent and an agent for bronchial asthma comprising the same; and a method for treatment of an allergic disease or bronchial asthma comprising the step of administering the same.
wherein Y represents an alkylene group having 1 to 7 carbon atoms; A is a group represented by formula I-a or formula I-b:
wherein X represents -CH₂-S- or -S-; and R represents a hydrogen atom or a lower alkyl group with a proviso that A is a group represented by formula I-a, or R represents a hydrogen atom with a proviso that A is a group represented by formula I-b and pharmacologically acceptable salts thereof are disclosed. Also disclosed are a method for preparing the same; a pharmaceutical composition comprising the same; an antiallergic agent and an agent for bronchial asthma comprising the same; and a method for treatment of an allergic disease or bronchial asthma comprising the step of administering the same.
信息查询
