发明公开
EP0453054A2 Antigenic proteins and vaccines containing them for prevention of coccidiosis
失效
含有它们的抗原蛋白质和疫苗用于预防球虫病
- 专利标题： Antigenic proteins and vaccines containing them for prevention of coccidiosis
- 专利标题（中）： 含有它们的抗原蛋白质和疫苗用于预防球虫病
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申请号： EP91201751.4申请日： 1986-11-24
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公开(公告)号： EP0453054A2公开(公告)日： 1991-10-23
- 发明人: Newman, Karel Z., Jr. , Gore, Thomas C. , Tedesco, John L. , Petersen, Gary R. , Brothers, Virginia M. , Files, James G. , Paul, Leland S. , Chang, Ray-Jen , Andrews, William H. , Kuhn, Irene , McCaman, Michael , Sias, Stacey R. , Nordgren, Robert M. , Dragon, Elizabeth A.
- 申请人： SOLVAY (Société Anonyme)
- 申请人地址： Rue du Prince Albert, 33 B-1050 Bruxelles BE
- 专利权人： SOLVAY (Société Anonyme)
- 当前专利权人： SOLVAY (Société Anonyme)
- 当前专利权人地址： Rue du Prince Albert, 33 B-1050 Bruxelles BE
- 代理机构： Lechien, Monique
- 优先权： US805301 19851203; US805824 19851206; US807497 19851211; US808013 19851211
- 主分类号： C12N15/30
- IPC分类号： C12N15/30 ; C12N15/62 ; C12P21/00 ; A61K39/012
摘要：
Purified antigenic proteins are provided which are capable of inducing in a chicken an immune response conferring protection against infection by Eimeria necatrix and/or Eimeria tenella. One protein, useful for conferring protection against E. tenella and E. necatrix, has been derived from sporocysts of E. necatrix.
Monoclonal antibodies directed against the antigenic proteins have also been developed which may be used to confer upon a chicken passive immunity against coccidiosis.
Further provided are nucleic acid molecules encoding the antigenic proteins as well as expression vectors containing them. Methods for producing the proteins or antigenic polypeptides having amino acid sequences included within these proteins are also provided.
Monoclonal antibodies directed against the antigenic proteins have also been developed which may be used to confer upon a chicken passive immunity against coccidiosis.
Further provided are nucleic acid molecules encoding the antigenic proteins as well as expression vectors containing them. Methods for producing the proteins or antigenic polypeptides having amino acid sequences included within these proteins are also provided.
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