发明公开
- 专利标题: Recombinant adenovirus vaccines
- 专利标题(中): Rekombinente Adenoviren-Impfstoffe。
-
申请号: EP93305833.1申请日: 1993-07-23
-
公开(公告)号: EP0586076A2公开(公告)日: 1994-03-09
- 发明人: Davis, Alan Robert , Hunt, Paul Porwen , Lubeck, Micheal David , Natuk, Robert James , Chanda, Pranab Kumar , Murthy, Shridhara Chikkatur Shankaranarayana , Lee, Shaw-Guang Lin
- 申请人: AMERICAN HOME PRODUCTS CORPORATION
- 申请人地址: Five Giralda Farms Madison, New Jersey 07940-0874 US
- 专利权人: AMERICAN HOME PRODUCTS CORPORATION
- 当前专利权人: AMERICAN HOME PRODUCTS CORPORATION
- 当前专利权人地址: Five Giralda Farms Madison, New Jersey 07940-0874 US
- 代理机构: Connelly, Michael John
- 优先权: US926491 19920807
- 主分类号: C12N15/86
- IPC分类号: C12N15/86 ; C12N15/49 ; A61K39/21 ; C12N7/01 ; C07K13/00
摘要:
The production of antibodies or cell mediated immunity to an infectious organism in a warm blooded mammal is disclosed. The production comprises administering to the said warm blooded mammal intranasally, intramuscularly, or subcutaneously, live recombinant adenoviruses in which the virion structural protein is unchanged from that in the native adenovirus from which the recombinant adenovirus is produced, and which contain the gene coding for the antigen corresponding to said antibodies or inducing said cell mediated immunity. Vaccines containing the live recombinant adenoviruses are also described. Some of the recombinant adenoviruses are new per se .
公开/授权文献
- EP0586076B1 Recombinant adenovirus vaccines 公开/授权日:2003-06-25
信息查询
IPC分类: