发明公开
- 专利标题： IMMUNIZATION BY INOCULATIOON OF DNA TRANSCRIPTION UNIT
- 专利标题（中）： 与DNA转录单位IMMUNIZIERUNG通过接种疫苗。
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申请号： EP93907536.0申请日： 1993-03-17
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公开(公告)号： EP0633937A1公开(公告)日： 1995-01-18
- 发明人: ROBINSON, Harriet, L. , FYNAN, Ellen, F. , WEBSTER, Robert, G.
- 申请人： UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER
- 申请人地址： 55 Lake Avenue North Worcester, MA 01655 US
- 专利权人： UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER
- 当前专利权人： UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER
- 当前专利权人地址： 55 Lake Avenue North Worcester, MA 01655 US
- 代理机构： Harvey, David Gareth, et al
- 优先权： US19920855562 19920323; US19930009833 19930127
- 国际公布： WO1993019183 19930930
- 主分类号： A61K48
- IPC分类号： A61K48 ; A61K9 ; A61K35 ; A61K39 ; A61P15 ; A61P31 ; A61P33 ; A61P35 ; C07K14 ; C12N15 ; A61K38 ; C12R1
摘要：
This invention relates to a method of immunizing a vertebrate, comprising introducing into the vertebrate a DNA transcription unit which comprises DNA encoding a desired antigen or antigens. The uptake of the DNA transcription unit by a host vertebrate results in the expression of the desired antigen or antigens, thereby eliciting humoral or cell-mediated immune responses or both humoral and cell-mediated responses. The elicited humoral and cell-mediated immune response can provide protection against infection by pathogenic agents, provide an anti-tumor response, or provide contraception. The host can be any vertebrate, avian or mammal, including humans.
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